The flesh and blood of Ghouls and Vampires have long been used in a Necrofex's creation, suffusing it with even greater life, but forcing it to suffer from a black hunger it cannot satiate.
Source: Warhammer Armies Project: Unofficial 9th Edition (v2.2)
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The Necrofex Colossus gains the Regeneration (3+) special rule, but is also subject to the Berserk Rage part of Frenzy.